Insights to power better bladder cancer care.
We are collecting some of the most robust clinical data and largest observational cohorts ever obtained in urothelial cancer to further expand the clinical utility of UroAmp beyond detection, monitoring, and prediction. Our published data is highly compelling, and we are committed to doing even more.
Publications
More than 40 abstracts at major conferences
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Journal of Urology 2026
Urine Tumor DNA Testing Identifies Recurrence and Monitors Therapy Response in Patients with High-Risk Non–Muscle-Invasive Bladder Cancer Receiving Intravesical Bacillus Calmette-Guérin
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European Urology Focus 2026
Performance of Urine Tumor DNA Detection in Patients with High-grade Non–muscle-invasive Bladder Cancer Undergoing Repeat Transurethral Resection
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Journal of Clinical Oncology 2025
Gemcitabine Intravesical System Plus Cetrelimab or Cetrelimab Alone as Neoadjuvant Therapy in Muscle-Invasive Bladder Cancer: SunRISe-4 Primary Analysis and Biomarker Results
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European Urology 2025
Urine Tumor DNA to Stratify the Risk of Recurrence in Patients Treated with Atezolizumab for Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer
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European Urology Oncology 2025
Minimal Residual Disease Detection with Urine-derived DNA Is Prognostic for Recurrence-free Survival in Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer Treated with Nadofaragene Firadenovec
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Molecular Oncology 2023
Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy
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Frontiers in Urology 2023
Clinical utility of urinary comprehensive genomic profiling in diagnosing metachronous upper tract urothelial carcinoma: a case report
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Clinical Cancer Research 2023
Development and Multicenter Case–Control Validation of Urinary Comprehensive Genomic Profiling for Urothelial Carcinoma Diagnosis, Surveillance, and Risk-Prediction
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Journal of Clinical Medicine I 2022
Urinary comprehensive genomic profiling correlates urothelial carcinoma mutations with clinical risk and efficacy of intervention
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Convergent Multicenter
Clinical Trials
INSITE Study
(enrollment closed)
This study is powered to allow evaluation of many less common and fascinating populations of patients within the spectrum of bladder cancer, from diagnosis through treatment. The INSITE study will power deep evidence of UroAmp’s disease classification algorithms and genomic risk insights across diverse patient populations, time points, pathologic subtypes, and many other sub-analyses. Strength of the INSITE data will grow with long-term sample collections and monitoring of patient outcomes.
CURE Study
(enrollment closed)
The CURE study is a broad development and validation study enrolling patients with diverse clinical scenarios and abnormalities.
This study design is intended to prove our ability to detect multiple types of cancer from urine. CURE patients have been enrolled from urology offices with broad inclusion criteria. Many of these scenarios, such as infection and recent instrumentation, are direct contraindications to previous technologies. The CURE study will validate multi-cancer detection in a broad group of patients with diverse clinical co-morbidities and other.
Biopharma
Partnerships
We are committed to empowering our biopharmaceutical partners to assist them in delivering breakthrough therapeutics in precision oncology. Our technology can be used to inform trial design, identify ideal patients, and measure response and resistance to targeted therapeutics, potentially accelerating trial enrollment and improving program success rates.
